Can Aspirin really increase the pregnancy rate of women who suffer from chronic inflammation?

Although we normally focus on men, we thought this study could be an interesting read for our site visitors! While many couples are focusing on fertility solutions and trying a wide range of methods to conceive, researchers are offering new information that could help women who suffer from chronic inflammation. This research shows that a low dosage of aspirin, similar to what doctors prescribe men for heart health, can help increase the chance of conception.

What is Infertility?

The Centers for Disease Control and Prevention (CDC) report that an alarmingly high percentage of women around the world are infertile. To understand this, we must first understand the definition of infertility. Infertility can be defined as the inability to conceive after a period of 1 year of unprotected sexual intercourse. It can include either conceiving or maintaining a pregnancy and the cause can be attributed to either partner.

How does inflammation affect fertility?

Studies have shown that manywomen once thought to be infertile, suffer from chronic, low-grade inflammation, a common cause of infertility. Research conducted by the Eunice Kennedy Shriver National Institute of Child Health and Human Development studied the effects of low-dose aspirin on many factors including pregnancy rate, pregnancy loss, births and inflammation during pregnancy.

Their findings, which were published in The Journal of Clinical Endocrinology & Metabolism, propose that women who took a low daily dose of aspirin have a much higher conception rate than those who didn”t.

The study

The study, named the Effects of Aspirin in Gestation and Reproduction (EAGeR), was randomised, double blind and placebo controlled and was conducted on 1,228 women who were trying to conceive but had previously lost one or two pregnancies.

Each participant was administered a daily dose of 81 milligrams of aspirin while they were trying to conceive. The dosage was continued throughout the gestation period in the women who successfully conceived. Being a randomized trial, some of the women received aspirin and some of them received a placebo1 “https://www.nichd.nih.gov/about/org/diphr/eb/research/pages/effects-aspirin.aspx”.

The results

The women who took the low dose of aspirin had a 35% higher chance of conceiving. Aspirin has almost no side effects at these low dosages, and also provides other health benefits such aspossibly preventing heart attacks.

Although more testing is needed, researchers are confident that they can replicate their findings with other groups of women. If so, this could provide an effective solution for women everywhere who are having a difficult time conceiving.

Improve your fertility with micronutrients

Several micronutrients such as vitamins, vitaminoids, amino acids and trace elements have proven themselves effective in improving sperm quantity, mobility and shape. This directly translates into better overall sperm qualityand therefore a higher chance of pregnancy.

A natural food supplementation therapy for men is:

  • relatively inexpensive
  • effective after three to six months
  • able toincrease sperm motility by up to 23%, ejaculate volume by up to 33% and sperm count by up to 215%2 “Imhof, Martin et al., “Improvement of sperm quality after micronutritient supplementation”, e-SPEN, the European e-Journal of Clinical Nutrition and Metabolism, Epub published ahead of print.”
  • without side effects

For those reasons, male fertility food supplements are most definitely recommended as the first step in the treatment of oligospermia and asthenospermia.

Pregnancy test - happy surprised woman We have tested the best natural male fertility boosters[/caption[/mfn]

Also men who have not yet taken a semen analysis test will benefit from supplementing micronutrients to ensure they are able to deliver high-quality semen.

There are no contraindications or side effects to this form of natural “sperm boosting”.

An excellent and detailed overview of many studies can be found inSteven Sinclair’s Male Infertility: Nutritional and EnvironmentalConsiderations.

A considerable range of male fertility supplements available on the UK market.

However, the products differ widely in price and composition. Menfertility.org has compared 10 of them in terms of value for money and the nutrients they provide.

The most effective male fertility nutrients

A multitude of studies has shown that highly dosed nutrients have potentially significant impact on overall sperm quality.

The amino acidL-argininehas been proven to increase sperm count and motility 3 “http://www.altmedrev.com/publications/5/1/28.pdf” 4http://www.ncbi.nlm.nih.gov/pubmed/7701414.

Another amino acidL-carnitinehas been found to significantly improve sperm concentration (count) and motility over a relatively short period of only 8 weeks5http://www.ncbi.nlm.nih.gov/pubmed/12568837 6http://www.ncbi.nlm.nih.gov/pubmed/8085668.

Vitamin Dhas been shown to improve sperm count, motility and morphology7http://www.ncbi.nlm.nih.gov/pubmed/21427118.

Vitamin B9,better known asfolic acidhas been shown to increase count, motility and morphology8http://www.ncbi.nlm.nih.gov/pubmed/20978181.

Zincimproves the immune system and significantly improves sperm countin combination with folic acid9http://www.ncbi.nlm.nih.gov/pubmed/11872201.

Seleniumin combination withvitamin Ehas been found to improve motility10http://www.ncbi.nlm.nih.gov/pubmed/21403799 11http://www.ncbi.nlm.nih.gov/pubmed/12623744 12http://www.ncbi.nlm.nih.gov/pubmed/8862739.

Nutrients must be applied permanently

Sperm cells take 11 weeks to mature in the testicles. Only then they are ready for ejaculation.
If you adjust your diet today it will thus take three months for the better sperm to be ready for fertilisation.
You must therefore keep the diet or supplement on an ongoing basis – ideally until your partner is pregnant or you decide for a different treatment.

All of the male fertility supplements in our great test include several of these nutrients at once, albeit at a lower dose. This is a cost-effective and convenient way making this type of fertility therapyaffordable and requiring taking only one all-in-one supplement instead of many.

To find out more about the effects of the individual nutrients and how the various supplements compare, please read menfertility.org’s male fertility supplement review.

The top male fertility supplements

Bibliography

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